Clinical guideline recommendations for antipsychotic long-acting injections

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Clinical guideline recommendations for antipsychotic long-acting injections.

BACKGROUND Long-acting injections (LAIs) of antipsychotic drugs were developed over 40 years ago in an attempt to improve the long-term treatment of schizophrenia. AIMS To review existing guidelines concerning antipsychotic use generally, and LAIs in particular, and how patients might be identified as potential candidates for LAI treatment. METHOD Literature review. RESULTS Currently seve...

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Antipsychotic long-acting injections: mind the gap.

Long-acting injections of antipsychotic medication (or depots) were developed specifically to promote treatment adherence and are a valuable option for maintenance medication in psychotic illnesses. Approximately 40-60% of patients with schizophrenia are partially or totally non-adherent to their antipsychotic regimen, but only 30% or less are prescribed a long-acting injection. The use of such...

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Historical perspective on antipsychotic long-acting injections.

BACKGROUND Clinical experience has shown considerable potential benefits from long-term continuous medication for chronic or relapsing forms of schizophrenia. These benefits have not always been realised. AIMS To review the research literature in order to understand the problems of long-term medication and use of antipsychotic oral medication and long-acting injections (LAIs), and to place th...

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Community treatment orders and antipsychotic long-acting injections.

BACKGROUND The community treatment order (CTO) is the legal framework by which people in the community are compelled to accept treatment. Both antipsychotic long-acting injections (LAIs) and CTOs are used to address treatment non-adherence. AIMS To investigate the relationship between CTOs and LAI use in patients with schizophrenia. METHOD Prescribing, demographic and CTO data were collecte...

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Knowledge about antipsychotic long-acting injections: bridging that gap.

Antipsychotics in depot (or ;long-acting injection', LAI) form are shown in this supplement to be a significant component of clinical practice. They are comparatively underresearched, which may reflect their frequent use witih poorly adherent patients. This supplement clearly demonstrates the need for that research, highlighting the variations in dosing and the absence of established, specific ...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2009

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.195.52.s63